Publications

Find journal articles and other publications about the BOTTLE™ consortium research.

Featured Publications

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All Publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018

2024

Characterization of Polymer Properties and Identification of Additives in Commercially Available Research Plastics
Green Chemistry
March 26, 2024
Amy A. Cuthbertson, Clarissa Lincoln, Joel Miscall, Lisa M. Stanley, Anjani K. Maurya, Arun S. Asundi, Christopher J. Tassone, Nicholas A. Rorrer, Gregg T. Beckham

Recyclable and (Bio)degradable Polyesters in a Circular Plastics Economy
Chemical Reviews
March 22, 2024
Changxia Shi, Ethan C. Quinn, Wilfred T. Diment, Eugene Y.-X. Chen

Topology-Accelerated and Selective Cascade Depolymerization of Architecturally Complex Polyesters
Journal of the American Chemical Society
March 22, 2024
Changxia Shi, Nicholas A. Rorrer, Alexander L. Shaw, Ryan W. Clarke, Bonnie L. Buss, Gregg T. Beckham, Linda J. Broadbelt, Eugene Y.-X. Chen

Synthesis, Characterization, and Recycling of Bio-Derivable Polyester Covalently Adaptable Networks for Industrial Composite Applications
Matter
Feb. 7, 2024
Chen Wang, Avantika Singh, Erik G. Rognerud, Robynne Murray, Grant M. Musgrave, Morgan Skala, Paul Murdy, Jason S. DesVeaux, Scott R. Nicholson, Kylee Harris, Richard Canty, Fabian Mohr, Alison J. Shapiro, David Barnes, Ryan Beach, Robert D. Allen, Gregg T. Beckham, Nicholas A. Rorrer

Chemically Recyclable Nanofiltration Membranes Fabricated From Two Circular Polymer Classes of the Same Monomer Origin
Journal of Membrane Science Letters
Feb. 2, 2024
Rifan Hardian, Abdul Ghaffar, Changxia Shi, Eugene Y.-X. Chen, Gyorgy Szekely

2023

Elastomeric Vitrimers From Designer Polyhydroxyalkanoates With Recyclability and Biodegradability
Science Advances
Nov. 22, 2023
Robin M. Cywar, Chen Ling, Ryan W. Clarke, Dong Hyun Kim, Colin M. Kneucker, Davinia Salvachúa, Bennett Addison, Sarah A. Hesse, Christopher J. Takacs, Shu Xu, Meltem Urgun Demirtas, Sean P. Woodworth, Nicholas A. Rorrer, Christopher W. Johnson, Christopher J. Tassone, Robert D. Allen, Eugene Y.-X. Chen, Gregg T. Beckham

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Base-Mediated Depolymerization of Amine-Cured Epoxy Resins
ACS Sustainable Chemistry & Engineering
Nov. 20, 2023
Rebecca C. DiPucchio, Katherine R. Stevenson, Ciaran W. Lahive, William E. Michener, Gregg T. Beckham

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Toughening Brittle Bio-P3HB with Synthetic P3HB of Engineered Stereomicrostructures
Angewandte Chemie International Edition
Oct. 25, 2023
Zhen Zhang, Ethan C. Quinn, Jorge L. Olmedo-Martínez, Maria Rosaria Caputo, Kevin A. Franklin, Alejandro J. Müller, Eugene Y.-X. Chen

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Chemically Recyclable Polyolefin-Like Multiblock Polymers
Science
Oct. 19, 2023
Yucheng Zhao, Emma M. Rettner, Katherine L. Harry, Zhitao Hu, Joel Miscall, Nicholas A. Rorrer, Garret M. Miyake

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Chemical Upcycling of Polyethylene, Polypropylene, and Mixtures to High-Value Surfactants
Science
Aug. 10, 2023
Zhen Xu, Nuwayo Eric Munyaneza, Qikun Zhang, Mengqi Sun, Carlos Posada, Paul Venturo, Nicholas A. Rorrer, Joel Miscall, Bobby G. Sumpter, Guoliang Liu

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Effect of Ligand Chemistry on the Electronic Properties and Reactivity of Cobalt Acetate Autoxidation Catalysts
The Journal of Physical Chemistry
Aug. 2, 2023
Arun S. Asundi, Amani M. Ebrahim, Anjani K. Maurya, Chad T. Palumbo, Kevin P. Sullivan, Gregg T. Beckham, Ritimukta Sarangi

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Mono-Material Product Design With Bio-Based, Circular, and Biodegradable Polymers
One Earth
June 16, 2023
Ethan C. Quinn, Katrina M. Knauer, Gregg T. Beckham, Eugene Y.-X. Chen

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Techno-Economic Analysis and Life Cycle Assessment for Catalytic Fast Pyrolysis of Mixed Plastic Waste
Energy & Environmental Science
June 5, 2023
Geetanjali Yadav, Avantika Singh, Abhijit Dutta, Taylor Uekert, Jason DesVeaux, Scott R Nicholson, Eric C. D. Tan, Calvin Mukarakate, Joshua A Schaidle, Cody Wrasman, Alberta Carpenter, Robert Baldwin, Yuriy Román-Leshkov, Gregg T. Beckham

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Techno-Economic Analysis and Life Cycle Assessment of Mixed Plastic Waste Gasification for Production of Methanol and Hydrogen
Green Chemistry
May 31, 2023
Shaik Afzal, Avantika Singh, Scott R Nicholson, Taylor Uekert, Jason DesVeaux, Eric C. D. Tan, Abhijit Dutta, Alberta Carpenter, Robert Baldwin, Gregg T. Beckham

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Dual Recycling of Depolymerization Catalyst and Biodegradable Polyester That Markedly Outperforms Polyolefins
Angewandte Chemie International Edition
April 27, 2023
Xin-Lei Li, Ryan W. Clarke, Hai-Yan An, Ravikumar R. Gowda, Jing-Yang Jiang, Tie-Qi Xu, Eugene Y.-X. Chen

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Dynamic Crosslinking Compatibilizes Immiscible Mixed Plastics
Nature
April 26, 2023
Ryan W. Clarke, Tobias Sandmeier, Kevin A. Franklin, Dominik Reich, Xiao Zhang, Nayan Vengallur, Tarak K. Patra, Robert J. Tannenbaum, Sabin Adhikari, Sanat K. Kumar, Tomislav Rovis, Eugene Y.-X. Chen

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All-Polyhydroxyalkanoate Triblock Copolymers via a Stereoselective-Chemocatalytic Route
ACS Macro Letters
April 24, 2023
Andrea H. Westlie, Sarah A. Hesse, Xiaoyan Tang, Ethan C. Quinn, Celine R. Parker, Christopher J. Takacs, Christopher J. Tassone, Eugene Y.-X. Chen

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Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene Terephthalate) Can Be Eliminated by Enzyme Engineering
ChemSusChem
April 19, 2023
Luisana Avilan, Bruce R. Lichtenstein, Gerhard König, Michael Zahn, Mark D. Allen, Liliana Oliveira, Matilda Clark, Victoria Bemmer, Rosie Graham, Harry P. Austin, Graham Dominick, Christopher W. Johnson, Gregg T. Beckham, John E. McGeehan, Andrew R. Pickford

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Hybrid Monomer Design Synergizing Property Trade-Offs in Developing Polymers for Circularity and Performance
Angewandte Chemie International Edition
April 18, 2023
Changxia Shi, Liam T. Reilly, Eugene Y.-X. Chen

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Chemically Circular, Mechanically Tough, and Melt-Processable Polyhydroxyalkanoates
Science
April 6, 2023
Li Zhou, Zhen Zhang, Changxia Shi, Miriam Scoti, Deepak K. Barange, Ravikumar R. Gowda, Eugene Y.-X. Chen

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Installing Controlled Stereo-Defects Yields Semicrystalline and Biodegradable Poly(3-hydroxybutyrate) With High Toughness and Optical Clarity
Journal of the American Chemical Society
March 3, 2023
Ethan C. Quinn, Andrea H. Westlie, Ainara Sangroniz, Maria Rosaria Caputo, Shu Xu, Zhen Zhang, Meltem Urgun-Demirtas, Alejandro J. Müller, Eugene Y.-X. Chen

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Complex Regulation in a Comamonas Platform for Diverse Aromatic Carbon Metabolism
Nature Chemical Biology
Feb. 6, 2023
Rebecca A. Wilkes, Jacob Waldbauer, Austin Caroll, Manuel Nieto-Domínguez, Darren J. Parker, Lichun Zhang, Adam M. Guss, Ludmilla Aristilde

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Endowing Polythioester Vitrimer With Intrinsic Crystallinity and Chemical Recyclability
ChemSusChem
Jan. 13, 2023
Changxia Shi, Zhen Zhang, Miriam Scoti, Xiao-Yun Yan, Eugene Y.-X. Chen

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Technical, Economic, and Environmental Comparison of Closed-Loop Recycling Technologies for Common Plastics
ACS Sustainable Chemistry & Engineering
Jan. 12, 2023
Taylor Uekert, Avantika Singh, Jason S. DesVeaux, Tapajyoti Ghosh, Arpit Bhatt, Geetanjali Yadav, Shaik Afzal, Julien Walzberg, Katrina M. Knauer, Scott R. Nicholson, Gregg T. Beckham, Alberta C. Carpenter

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2022

Sourcing Thermotolerant Poly(Ethylene Terephthalate) Hydrolase Scaffolds From Natural Diversity
Nature Communications
Dec. 21, 2022
Erika Erickson, Japheth E. Gado, Luisana Avilán, Felicia Bratti, Richard K. Brizendine, Paul A. Cox, Raj Gill, Rosie Graham, Dong-Jin Kim, Gerhard König, William E. Michener, Saroj Poudel, Kelsey J. Ramirez, Thomas J. Shakespeare, Michael Zahn, Eric S. Boyd, Christina M. Payne, Jennifer L. DuBois, Andrew R. Pickford, Gregg T. Beckham, John E. McGeehan

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Tackling the Catch-22 Situation of Optimizing a Sensor and a Transporter System in a Whole-Cell Microbial Biosensor Design for an Anthropogenic Small Molecule
ACS Synthetic Biology
Dec. 6, 2022
Sang-Min Shin, Ramesh K. Jha, Taraka Dale

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Selective Lanthanide-Organic Catalyzed Depolymerization of Nylon-6 to ϵ-Caprolactam
Angewandte Chemie International Edition
Nov. 28, 2022
Lukas Wursthorn, Kristen Beckett, Jacob O. Rothbaum, Robin M. Cywar, Clarissa Lincoln, Yosi Kratish, Tobin J. Marks

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Synthetic Biodegradable Polyhydroxyalkanoates (PHAs): Recent Advances and Future Challenges
Progress in Polymer Science
November 2022
Andrea H. Westlie, Ethan C. Quinn, Celine R. Parker, Eugene Y.-X. Chen

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Catalytic Production of Tetrahydropyran (THP): A Biomass-Derived, Economically Competitive Solvent With Demonstrated Use in Plastic Dissolution
Green Chemistry
Nov. 8, 2022
Raka G. Dastidar, Min Soo Kim, Panzheng Zhou, Zaneta Luo, Changxia Shi, Kevin J. Barnett, Daniel J. McClelland, Eugene Y.-X. Chen, Reid C. Van Lehn, George W. Huber

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Role of Bifunctional Ru/Acid Catalysts in the Selective Hydrocracking of Polyethylene and Polypropylene Waste to Liquid Hydrocarbons
ACS Catalysis
Oct. 31, 2022
Julie E. Rorrer, Amani M. Ebrahim, Ydna Questell-Santiago, Jie Zhu, Clara Troyano-Valls, Arun S. Asundi, Anna E. Brenner, Simon R. Bare, Christopher J. Tassone, Gregg T. Beckham, Yuriy Román-Leshkov

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Mixed Plastics Waste Valorization Through Tandem Chemical Oxidation and Biological Funneling
Science
Oct. 13, 2022
Kevin P. Sullivan, Allison Z. Werner, Kelsey J. Ramirez, Lucas D. Ellis, Jeremy R. Bussard, Brenna A. Black, David G. Brandner, Felicia Bratti, Bonnie L. Buss, Xueming Dong, Stefan J. Haugen, Morgan A. Ingraham, Mikhail O. Konev, William E. Michener, Joel Miscall, Isabel Pardo, Sean P. Woodworth, Adam M. Guss, Yuriy Román-Leshkov, Shannon S. Stahl, Gregg T. Beckham

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Alternating Isotactic Polyhydroxyalkanoates via Site- and Stereo-Selective Polymerization of Unsymmetrical Diolides
Journal of the American Chemical Society
Oct. 8, 2022
Zhen Zhang, Changxia Shi, Miriam Scoti, Xiaoyan Tang, Eugene Y.-X. Chen

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The Role of Binding Modules in Enzymatic Poly(Ethylene Terephthalate) Hydrolysis at High-Solids Loadings
Chem Catalysis
Aug. 23, 2022
Rosie Graham, Erika Erickson, Richard K. Brizendine, Davinia Salvachúa, William E. Michener, Yaohao Li, Zhongping Tan, Gregg T. Beckham, John E. McGeehan, Andrew R. Pickford

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Life Cycle Assessment of Enzymatic Poly(Ethylene Terephthalate) Recycling
Green Chemistry
Aug. 2, 2022
Taylor Uekert, Jason S. DesVeaux, Avantika Singh, Scott R. Nicholson, Patrick Lamers, Tapajyoti Ghosh, John E. McGeehan, Alberta C. Carpenter, Gregg T. Beckham

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Polyolefin Innovations Toward Circularity and Sustainable Alternatives
Macromolecular Rapid Communications
July 30, 2022
Andrea H. Westlie, Eugene Y.-X. Chen, Chris M. Holland, Shannon S. Stahl, Meredith Doyle, Scott R. Trenor, Katrina M. Knauer

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Particle Size Reduction of Poly(ethylene terephthalate) Increases the Rate of Enzymatic Depolymerization But Does Not Increase the Overall Conversion Extent
ACS Sustainable Chemistry & Engineering
July 7, 2022
Richard K. Brizendine, Erika Erickson, Stefan J. Haugen, Kelsey J. Ramirez, Joel Miscall, Davinia Salvachúa, Andrew R. Pickford, Margaret J. Sobkowicz, John E. McGeehan, Gregg T. Beckham

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Reaction-Mediated Transformation of Working Catalysts
ACS Catalysis
June 21, 2022
Gang Wan, Guanghui Zhang, Johnny Zhu Chen, Michael F. Toney, Jeffrey T. Miller, Christopher J. Tassone

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Critical Advances and Future Opportunities in Upcycling Commodity Polymers
Nature
March 30, 2022
Coralie Jehanno, Jill W. Alty, Martijn Roosen, Steven De Meester, Andrew P. Dove, Eugene Y.-X. Chen, Frank A. Leibfarth, Haritz Sardon

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Biochemical and Structural Characterization of an Aromatic Ring–Hydroxylating Dioxygenase for Terephthalic Acid Catabolism
Proceedings of the National Academy of Sciences
March 21, 2022
William M. Kincannon, Michael Zahn, Rita Clare , Jessica Lusty Beech, Ari Romberg, James Larson, Brian Bothner, Gregg T. Beckham, John E. McGeehan, Jennifer L. DuBois

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Redesigned Hybrid Nylons With Optical Clarity and Chemical Recyclability
Journal of the American Chemical Society
March 15, 2022
Robin M. Cywar, Nicholas A. Rorrer, Heather B. Mayes, Anjani K. Maurya, Christopher J. Tassone, Gregg T. Beckham, Eugene Y.-X. Chen

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A Flexible Kinetic Assay Efficiently Sorts Prospective Biocatalysts for PET Plastic Subunit Hydrolysis
RSC Advances
March 14, 2022
Jessica Lusty Beech, Rita Clare, William M. Kincannon, Erika Erickson, John E. McGeehan, Gregg T. Beckham, Jennifer L. DuBois

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Closing the “One Monomer–Two Polymers–One Monomer” Loop via Orthogonal (De)polymerization of a Lactone/Olefin Hybrid
Journal of the American Chemical Society
Jan. 27, 2022
Changxia Shi, Ryan W. Clarke, Michael L. McGraw, Eugene Y.-X. Chen

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2021

Electrochemical Activation of C−C Bonds Through Mediated Hydrogen Atom Transfer Reactions
ChemSusChem
Dec. 19, 2021
Bing Yan, Changxia Shi, Gregg T. Beckham, Eugene Y.-X. Chen, Yuriy Román-Leshkov

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Design Principles for Intrinsically Circular Polymers With Tunable Properties
Chem
Nov. 11, 2021
Changxia Shi, Liam T. Reilly, V. Sai Phani Kumar, Matthew W. Coile, Scott R. Nicholson, Linda J. Broadbelt, Gregg T. Beckham, Eugene Y.-X. Chen

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Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation
ChemSusChem
Sept. 29, 2021
Erika Erickson, Thomas J. Shakespeare, Felicia Bratti, Bonnie L. Buss, Rosie Graham, McKenzie A. Hawkins, Gerhard König, William E Michener, Joel Miscall, Kelsey J. Ramirez, Nicholas A. Rorrer, Michael Zahn, Andrew R. Pickford, John E. McGeehan, Gregg Beckham

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Bio-Based Polymers With Performance-Advantaged Properties
Nature Reviews Materials
Sept. 23, 2021
Robin M. Cywar, Nicholas A. Rorrer, Caroline B. Hoyt, Gregg T. Beckham, Eugene Y.-X. Chen

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Techno-Economic, Life-Cycle, and Socioeconomic Impact Analysis of Enzymatic Recycling of Poly(Ethylene Terephthalate)
Joule
Sept. 15, 2021
Avantika Singh, Nicholas A. Rorrer, Scott R. Nicholson, Erika Erickson, Jason S. DesVeaux, Andre F.T. Avelino, Patrick Lamers, Arpit Bhatt, Yi Min Zhang, Greg Avery, Ling Tao, Andrew R. Pickford, Alberta C. Carpenter, John E. McGeehan, Gregg T. Beckham

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Hydrogenolysis of Polypropylene and Mixed Polyolefin Plastic Waste Over Ru/C To Produce Liquid Alkanes
ACS Sustainable Chemistry & Engineering
July 27, 2021
Julie E. Rorrer, Clara Troyano-Valls, Gregg T. Beckham, and Yuriy Román-Leshkov

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Chemical and Biological Catalysis for Plastics Recycling and Upcycling
Nature Catalysis
July 22, 2021
Lucas D. Ellis, Nicholas A. Rorrer, Kevin P. Sullivan, Maike Otto, John E. McGeehan, Yuriy Román-Leshkov, Nick Wierckx, Gregg T. Beckham

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Tandem Chemical Deconstruction and Biological Upcycling of Poly(Ethylene Terephthalate) to β-Ketoadipic Acid by Pseudomonas putida KT2440
Metabolic Engineering
July 12, 2021
Allison Z. Werner, Rita Clare, Thomas D. Mand, Isabel Pardo, Kelsey J. Ramirez, Stefan J. Haugen, Felicia Bratti, Gara N. Dexter, Joshua R. Elmore, Jay D. Huenemann, George L. Peabody V, Christopher W. Johnson, Nicholas A. Rorrer, Davinia Salvachúa, Adam M. Guss, Gregg T. Beckham

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Manufacturing Energy and Greenhouse Gas Emissions Associated With Plastics Consumption
Joule
March 17, 2021
Scott R. Nicholson, Nicholas A. Rorrer, Alberta C. Carpenter, Gregg T. Beckham

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Hybrid Monomer Design for Unifying Conflicting Polymerizability, Recyclability, and Performance Properties
Chem
March 11, 2021
Changxia Shi, Zi-Chen Li, Lucia Caporaso, Luigi Cavallo, Laura Falivene, Eugene Y.-X. Chen

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Tandem Heterogeneous Catalysis for Polyethylene Depolymerization via an Olefin-Intermediate Process
ACS Sustainable Chemistry & Engineering
Jan. 8, 2021
Lucas D. Ellis, Sara V. Orski, Grace A. Kenlaw, Andrew G. Norman, Kathryn L. Beers, Yuriy Román-Leshkov, Gregg T. Beckham

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2020

Conversion of Polyolefin Waste to Liquid Alkanes with Ru-Based Catalysts under Mild Conditions
Journal of the American Chemical Society Au
Dec. 21, 2020
Julie E. Rorrer, Gregg T. Beckham, Yuriy Román-Leshkov

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Characterization and Engineering of a Two-Enzyme System for Plastics Depolymerization
Proceedings of the National Academy of Sciences
Sept. 28, 2020
Brandon C. Knott, Erika Erickson, Mark D. Allen, Japheth E. Gado, Rosie Graham, Fiona L. Kearns, Isabel Pardo, Ece Topuzlu, Jared J. Anderson, Harry P. Austin, Graham Dominick, Christopher W. Johnson, Nicholas A. Rorrer, Caralyn J. Szostkiewicz, Valérie Copié, Christina M. Payne, H. Lee Woodcock, Bryon S. Donohoe, Gregg T. Beckham, John E. McGeehan

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High-Performance Pan-Tactic Polythioesters With Intrinsic Crystallinity and Chemical Recyclability
Science Advances
Aug. 19, 2020
Changxia Shi, Michael L. McGraw, Zi-Chen Li, Luigi Cavallo, Laura Falivene, Eugene Y.-X. Chen

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Improving Enzyme Optimum Temperature Prediction With Resampling Strategies and Ensemble Learning
Journal of Chemical Information and Modeling
July 8, 2020
Japheth E. Gado, Gregg T. Beckham, Christina M. Payne

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High Chemical Recyclability of Vinyl Lactone Acrylic Bioplastics
Polymer Chemistry
July 1, 2020
Reid A. Gilsdorf, Matthew A. Nicki, Eugene Y.-X. Chen

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2019

Combining Reclaimed PET With Bio-based Monomers Enables Plastics Upcycling
Joule
April 17, 2019
Nicholas A. Rorrer, Scott Nicholson, Alberta Carpenter, Mary J. Biddy, Nicholas J. Grundl, Gregg T. Beckham

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2018

Characterization and Engineering of a Plastic-Degrading Aromatic Polyesterase
Proceedings of the National Academy of Sciences
April 17, 2018
Harry P. Austin, Mark D. Allen, Bryon S. Donohoe, Nicholas A. Rorrer, Fiona L. Kearns, Rodrigo L. Silveira, Benjamin C. Pollard, Graham Dominick, Ramona Duman, Kamel El Omari, Vitaliy Mykhaylyk, Armin Wagner, William E. Michener, Antonella Amore, Munir S. Skaf, Michael F. Crowley, Alan W. Thorne, Christopher W. Johnson, H. Lee Woodcock, John E. McGeehan, Gregg T. Beckham