Publications

Find journal articles and other publications about the BOTTLE™ consortium research.

Featured Publications

Strategy to orthogonally render two well-known low-ceiling-temperature (LCT) monomers—γ-butyrolactone toward ring-opening polymerization (ROP) to polyester and cyclohexene toward ring-opening metathesis polymerization (ROMP) to poly(cyclic olefin)—by creating an LCT/LCT hybrid, bicyclic lactone/olefin. This hybrid monomer undergoes orthogonal polymerization between ROP and ROMP, depending on the catalyst employed. Both are thermally robust but chemically recyclable under mild conditions to recover cleanly the same monomer via chain unzipping and scission.

Closing the "One Monomer–Two Polymers–One Monomer" Loop via Orthogonal (De)polymerization of a Lactone/Olefin Hybrid
Journal of the American Chemical Society
Jan. 27, 2022
Changxia Shi, Ryan W. Clarke, Michael L. McGraw, Eugene Y.-X. Chen


ChemSusChem 1/2022 publication cover

Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation
ChemSusChem
Sept. 29, 2021
Erika Erickson, Thomas J. Shakespeare, Felicia Bratti, Bonnie L. Buss, Rosie Graham, McKenzie A. Hawkins, Gerhard König, William E Michener, Joel Miscall, Kelsey J. Ramirez, Nicholas A. Rorrer, Michael Zahn, Andrew R. Pickford, John E. McGeehan, Gregg Beckham


ACS publication cover

Hydrogenolysis of Polypropylene and Mixed Polyolefin Plastic Waste Over Ru/C To Produce Liquid Alkanes
ACS Sustainable Chemistry & Engineering
July 27, 2021
Julie E. Rorrer, Clara Troyano-Valls, Gregg T. Beckham, and Yuriy Román-Leshkov


Chemical and Biological Catalysis for Plastics Recycling and Upcycling
Nature Catalysis
July 22, 2021
Lucas D. Ellis, Nicholas A. Rorrer, Kevin P. Sullivan, Maike Otto, John E. McGeehan, Yuriy Román-Leshkov, Nick Wierckx, Gregg T. Beckham


All Publications

2022

Life Cycle Assessment of Enzymatic Poly(Ethylene Terephthalate) Recycling
Green Chemistry
Aug. 2, 2022
Taylor Uekert, Jason S. DesVeaux, Avantika Singh, Scott R. Nicholson, Patrick Lamers, Tapajyoti Ghosh, John E. McGeehan, Alberta C. Carpenter, Gregg T. Beckham


Particle Size Reduction of Poly(ethylene terephthalate) Increases the Rate of Enzymatic Depolymerization But Does Not Increase the Overall Conversion Extent
ACS Sustainable Chemistry & Engineering
July 7, 2022
Richard K. Brizendine, Erika Erickson, Stefan J. Haugen, Kelsey J. Ramirez, Joel Miscall, Davinia Salvachúa, Andrew R. Pickford, Margaret J. Sobkowicz, John E. McGeehan, Gregg T. Beckham


Reaction-Mediated Transformation of Working Catalysts
ACS Catalysis
June 21, 2022
Gang Wan, Guanghui Zhang, Johnny Zhu Chen, Michael F. Toney, Jeffrey T. Miller, Christopher J. Tassone


Critical Advances and Future Opportunities in Upcycling Commodity Polymers
Nature
March 30, 2022
Coralie Jehanno, Jill W. Alty, Martijn Roosen, Steven De Meester, Andrew P. Dove, Eugene Y.-X. Chen, Frank A. Leibfarth, Haritz Sardon


Biochemical and Structural Characterization of an Aromatic Ring–Hydroxylating Dioxygenase for Terephthalic Acid Catabolism
Proceedings of the National Academy of Sciences
March 21, 2022
William M. Kincannon, Michael Zahn, Rita Clare , Jessica Lusty Beech, Ari Romberg, James Larson, Brian Bothner, Gregg T. Beckham, John E. McGeehan, Jennifer L. DuBois


Redesigned Hybrid Nylons With Optical Clarity and Chemical Recyclability
Journal of the American Chemical Society
March 15, 2022
Robin M. Cywar, Nicholas A. Rorrer, Heather B. Mayes, Anjani K. Maurya, Christopher J. Tassone, Gregg T. Beckham, Eugene Y.-X. Chen


A Flexible Kinetic Assay Efficiently Sorts Prospective Biocatalysts for PET Plastic Subunit Hydrolysis
RSC Advances
March 14, 2022
Jessica Lusty Beech, Rita Clare, William M. Kincannon, Erika Erickson, John E. McGeehan, Gregg T. Beckham, Jennifer L. DuBois


Closing the “One Monomer–Two Polymers–One Monomer” Loop via Orthogonal (De)polymerization of a Lactone/Olefin Hybrid
Journal of the American Chemical Society
Jan. 27, 2022
Changxia Shi, Ryan W. Clarke, Michael L. McGraw, Eugene Y.-X. Chen


2021

Design Principles for Intrinsically Circular Polymers With Tunable Properties
Chem
Nov. 11, 2021
Changxia Shi, Liam T. Reilly, V. Sai Phani Kumar, Matthew W. Coile, Scott R. Nicholson, Linda J. Broadbelt, Gregg T. Beckham, Eugene Y.-X. Chen


Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation
ChemSusChem
Sept. 29, 2021
Erika Erickson, Thomas J. Shakespeare, Felicia Bratti, Bonnie L. Buss, Rosie Graham, McKenzie A. Hawkins, Gerhard König, William E Michener, Joel Miscall, Kelsey J. Ramirez, Nicholas A. Rorrer, Michael Zahn, Andrew R. Pickford, John E. McGeehan, Gregg Beckham


Bio-Based Polymers With Performance-Advantaged Properties
Nature Reviews Materials
Sept. 23, 2021
Robin M. Cywar, Nicholas A. Rorrer, Caroline B. Hoyt, Gregg T. Beckham, Eugene Y.-X. Chen


Techno-Economic, Life-Cycle, and Socioeconomic Impact Analysis of Enzymatic Recycling of Poly(Ethylene Terephthalate)
Joule
Sept. 15, 2021
Avantika Singh, Nicholas A. Rorrer, Scott R. Nicholson, Erika Erickson, Jason S. DesVeaux, Andre F.T. Avelino, Patrick Lamers, Arpit Bhatt, Yi Min Zhang, Greg Avery, Ling Tao, Andrew R. Pickford, Alberta C. Carpenter, John E. McGeehan, Gregg T. Beckham


Hydrogenolysis of Polypropylene and Mixed Polyolefin Plastic Waste Over Ru/C To Produce Liquid Alkanes
ACS Sustainable Chemistry & Engineering
July 27, 2021
Julie E. Rorrer, Clara Troyano-Valls, Gregg T. Beckham, and Yuriy Román-Leshkov


Chemical and Biological Catalysis for Plastics Recycling and Upcycling
Nature Catalysis
July 22, 2021
Lucas D. Ellis, Nicholas A. Rorrer, Kevin P. Sullivan, Maike Otto, John E. McGeehan, Yuriy Román-Leshkov, Nick Wierckx, Gregg T. Beckham


Tandem Chemical Deconstruction and Biological Upcycling of Poly(Ethylene Terephthalate) to β-Ketoadipic Acid by Pseudomonas putida KT2440
Metabolic Engineering
July 12, 2021
Allison Z. Werner, Rita Clare, Thomas D. Mand, Isabel Pardo, Kelsey J. Ramirez, Stefan J. Haugen, Felicia Bratti, Gara N. Dexter, Joshua R. Elmore, Jay D. Huenemann, George L. Peabody V, Christopher W. Johnson, Nicholas A. Rorrer, Davinia Salvachúa, Adam M. Guss, Gregg T. Beckham


Manufacturing Energy and Greenhouse Gas Emissions Associated With Plastics Consumption
Joule
March 17, 2021
Scott R. Nicholson, Nicholas A. Rorrer, Alberta C. Carpenter, Gregg T. Beckham


Hybrid Monomer Design for Unifying Conflicting Polymerizability, Recyclability, and Performance Properties
Chem
March 11, 2021
Changxia Shi, Zi-Chen Li, Lucia Caporaso, Luigi Cavallo, Laura Falivene, Eugene Y.-X. Chen


Tandem Heterogeneous Catalysis for Polyethylene Depolymerization via an Olefin-Intermediate Process
ACS Sustainable Chemistry & Engineering
Jan. 8, 2021
Lucas D. Ellis, Sara V. Orski, Grace A. Kenlaw, Andrew G. Norman, Kathryn L. Beers, Yuriy Román-Leshkov, Gregg T. Beckham


2020

Conversion of Polyolefin Waste to Liquid Alkanes with Ru-Based Catalysts under Mild Conditions
JACS Au
Dec. 21, 2020
Julie E. Rorrer, Gregg T. Beckham, Yuriy Román-Leshkov


Characterization and Engineering of a Two-Enzyme System for Plastics Depolymerization
Proceedings of the National Academy of Sciences
Sept. 28, 2020
Brandon C. Knott, Erika Erickson, Mark D. Allen, Japheth E. Gado, Rosie Graham, Fiona L. Kearns, Isabel Pardo, Ece Topuzlu, Jared J. Anderson, Harry P. Austin, Graham Dominick, Christopher W. Johnson, Nicholas A. Rorrer, Caralyn J. Szostkiewicz, Valérie Copié, Christina M. Payne, H. Lee Woodcock, Bryon S. Donohoe, Gregg T. Beckham, John E. McGeehan


High-Performance Pan-Tactic Polythioesters With Intrinsic Crystallinity and Chemical Recyclability
Science Advances
Aug. 19, 2020
Changxia Shi, Michael L. McGraw, Zi-Chen Li, Luigi Cavallo, Laura Falivene, Eugene Y.-X. Chen


Improving Enzyme Optimum Temperature Prediction With Resampling Strategies and Ensemble Learning
Journal of Chemical Information and Modeling
July 8, 2020
Japheth E. Gado, Gregg T. Beckham, Christina M. Payne


High Chemical Recyclability of Vinyl Lactone Acrylic Bioplastics
Polymer Chemistry
July 1, 2020
Reid A. Gilsdorf, Matthew A. Nicki, Eugene Y.-X. Chen


2019

Combining Reclaimed PET With Bio-based Monomers Enables Plastics Upcycling
Joule
April 17, 2019
Nicholas A. Rorrer, Scott Nicholson, Alberta Carpenter, Mary J. Biddy, Nicholas J. Grundl, Gregg T. Beckham


2018

Characterization and Engineering of a Plastic-Degrading Aromatic Polyesterase
Proceedings of the National Academy of Sciences
April 17, 2018
Harry P. Austin, Mark D. Allen, Bryon S. Donohoe, Nicholas A. Rorrer, Fiona L. Kearns, Rodrigo L. Silveira, Benjamin C. Pollard, Graham Dominick, Ramona Duman, Kamel El Omari, Vitaliy Mykhaylyk, Armin Wagner, William E. Michener, Antonella Amore, Munir S. Skaf, Michael F. Crowley, Alan W. Thorne, Christopher W. Johnson, H. Lee Woodcock, John E. McGeehan, Gregg T. Beckham